Part 2: Health apps, wearables, and sensors: The advancing frontier of digital health

Romney made last-minute visits to Ohio and Pennsylvania on Tuesday to try to drive up turnout in those states, while Vice President Joe Biden was dispatched to Ohio. Obama remained in his hometown of Chicago.
[slaut?]
我照顾好自己了吗?有时候,我们太过于关心他人从而忘记了去照顾自己。这很容易就把自己遗忘。
报告称,去年销售的手机大部分是预装安卓系统和支持4G的智能手机。
科森重塑了卡瑞尔的鼻子,把它变成鹰钩鼻。他还把卡瑞尔的发际线往后刮了一点,留出更多额头。
3.《绝望主妇》灵感来源于安德烈·耶茨案
这项任命是由澳大利亚贸易、旅游与投资部长史蒂文·乔博于2月21日宣布的。中国国家旅游局局长李金早出席了该活动。
swimming;Synchronised swimming;diving;canoeing;Whitewater slalom;Still Water;Rowing;Sailing;Water Ball
decline
Despite the breakthrough, Jack Ma, chairman of Alibaba Group, said there was no need for human beings to fear machines.
In the Robot World Cup Soccer final on June 30th the Dutch robots weren’t up against the Chinese team “Water” from Beijing. Within a minute the Chinese team scored a goal. The Dutch made an equalizer before half-time, yet in the second half team Water scored again.
“写这本书的一大挑战是异性恋男人能改变一个女人的生活并使她死心塌地的看法。”
The rise of populism, even in countries such as the US and UK where plenty of people are in work, has made politicians realise that the quality of jobs is as important as their quantity.
“听起来,哈佛对学生的私生活管得太宽了”,曾为OJ?辛普森等多位名人做过代理律师的德肖维茨说。
这也是短信应用独有的棘手问题。在消费内容时,我们希望广告乖乖待在一边。没人想在聊天时突然有条广告蹦出来。雷表示:“人们在聊天时最不想看到的就是打断对话的广告条或弹出式广告。可能这在非个人的网络上还管用,但在短信中,人们最恼火的就是看到传统广告。”
con共同,duct引导-引导大家的行为举止
5.3-D 打印耳朵
John Williams's classic score still raises goosebumps over 40 years after this summer blockbuster hit theaters. Jaws preys on our primal fear of the unknown in deep waters, showing a small beach town ravaged by a series of attacks from a single killer shark. In recent years, environmentalists have stressed the generally nonthreatening nature of sharks, which kill an average of just eight swimmers each year.
坚持依法全面履职。
在中国北方分析出的这种病毒与1957年以前传播的病毒相似,因此,1957年以前出生的人一般都有了抵抗力,而在那年之后出生的儿童和年轻人由于没有预先的免疫力而缺乏抵抗力。1978年这种病毒在世界各地传播开来,其中包括美国。这种病主要发生在孩子们身上,因此,这次流感没被看成是真正的大流行。1977-78年的流感季节,还没有及时地生产出控制病毒的疫苗,但是,1978-79年的流感疫苗就包含了这种病毒的疫苗。
站在舞台中央,莱昂纳多发言说:“这是无上的荣誉,对我意义重大。两年前当我们置身于荒野当中拍摄电影,我们深深地被大自然的美丽和庞杂所感染。
I don't know about you, but if I had a separate calendar for work, school and life, I'd be a complete mess. When everything in your life is on one calendar, in one planner, you can't double-book anything. You know, like an important test and a dinner with your boss.
[.m?ni'fest?u]
阿里巴巴旗下品牌淘宝位居第二,品牌价值429亿美元,超过了中国移动、百度和中国工商银行。
Chinese billionaire Wang Jianlin, whose company owns AMC Theaters climbed into the top 20.


变化世界中的得与失
与此同时,布拉德福德大学管理学院(Bradford University School of Management)和爱丁堡大学商学院(University of Edinburgh Business School)的排名均上升16位,分别排在第42名和第55名。剑桥大学(University of Cambridge)佳奇管理学院(Judge Business School)的排名上升15位,排在第14名。
科比·布莱恩特


With the increasing proliferation and sophistication of mobile phones, wearable devices such as smart watches, and sensors that can measure and gather a variety of data, public interest is growing in using consumer electronics to take ownership of personal health and wellness. A 2015 survey found that 66% of Americans age 66 and older want to use mobile technologies to improve their health by receiving medication reminders and tracking diet and nutrition, physical activity, and symptoms.[1

As a result, 39 percent of the post-90s generation tries to avoid the negative effects of mobile phone use through measures like turning off app notifications, intentionally limiting the frequency of social media interactions and staying away from social media entirely in certain situations.
Slow growth around the world won't hurt the U.S. all that much. American exports might flatten out or even dip, but that would be offset by lower imports of petroleum because of sinking oil prices. So the trade deficit is unlikely to get further out of whack.
要向依法依规的市场主体发出“前行、前行、再前行”的信号;向依靠劳动创业创新者亮起“可以、可以、再可以”的绿灯;对那些违法违规不良行为,就要及时亮出黄牌,甚至出红牌罚他下场。
['k?:p?rit]

Health apps and wearables
Health apps and wearables can unobtrusively gauge physiological and emotional states and collect, quantify, and monitor data regarding a user’s day-to-day behaviors. This “quantified self” can increase users’ self-awareness regarding their behavior and encourage positive changes to their overall health and well-being.[2] These commercially available devices also integrate an array of features to provide motivation through reward systems, opportunities for social in-teraction, tools for self-improvement, and prompts. The novelty, affordability, practicality, and ease of use have resulted in increased consumer enthusiasm and the pervasiveness of these devices.[3,4] With this growing interest in personal health, members of the general public are becoming more involved in monitoring and improving their own health habits.[5-10

Undoubtedly, merely tracking data through a device is not enough to maintain good health-related behaviors long-term, and the software must also incorporate motivational constructs important for the adoption and habituation of behaviors. For instance, a systematic review of studies that considered the use of electronic activity monitor systems found short-term changes in physical activity with self-monitoring, but no demonstration of superiority when the systems were compared with other interventions.[11] Another review of studies on the viability of using mobile technology for measuring and influencing physical activity found that most apps allow users to document their activity, set goals, review real-time feedback, connect to a social support network, and access online expertise.[12] However, less common among these apps were prompts to act and opportunities for problem solving and action planning, which are crucial constructs that translate intention into long-term behavior change.[13]

Sensor technologies
Sensor technologies have begun to enter the telehealth landscape and are primarily focused on continuous monitoring and precise diagnostics to inform management of various health conditions and diseases.[14-17] Sensors can be integrated into a watch or arm band or adhesive bandages and clothing, and then programmed to collect data on cardiac rhythm, heart rate, blood pressure, respiration, oxygen saturation, galvanic skin response, glucose levels, body temperature, body motions, ambient temperature, and global positioning. For health care providers, sensor inputs can permit remote monitoring, real-time teleconferencing, and timely care for patients with chronic diseases. For both patients and clinicians, telehealth supported by sensors can have profound implications. Clinicians can provide timely and patient-centred care to those living at a distance with chronic disease and can coordinate care when multiple providers are involved, reducing costs to the health care system.

A current clinical example is the management of paroxysmal atrial fibrillation with a mobile ECG and app that monitors the patient’s electrical rhythm to detect frequency and patterns of arrhythmias, and may even allow patients to share ultrasound and electrocardiogram data with their health care provider.[18-20] Telemonitoring with sensors can also support self-management of chronic diseases and detect early signs of deterioration in health requiring immediate treatment and advice.[21] Studies to date have demonstrated some clinical promise for the use of home telemonitoring in the context of heart failure and diabetes. A recent Cochrane review found that telemonitoring was an effective way to lower levels of glycated hemoglobin and low-density lipoprotein.[22] Although several studies on heart failure have produced conflicting results regarding the overall benefits of home monitoring,[23-26] systematic reviews have suggested that home telemonitoring reduces all-cause mortality and hospitalizations, and improves quality of life compared with usual care.[22,27] In addition, features such as automated and mobile telemonitoring appear to be more effective compared with other forms of home telemonitoring.[27]

Further studies are needed to determine how home health monitoring can improve patient safety during the transition from acute care to community care, and to examine the impact of home monitoring on health care costs. TEC4Home (Telehealth for Emergency-Community Continuity of Care Connectivity via Home Tele-monitoring), an initiative of the University of British Columbia and Vancouver Coastal Health, is seeking to do this with prospective trials designed to uncover how telemonitoring can support the safety of heart failure patients discharged from hospital to home.[28]

Mobile apps, wearables, and sensors in the clinical setting
Even though mobile apps, wearables, and sensor technologies are promising, further research is needed to validate their use and long-term impact.[29] This research will require the collaboration of clinicians, health researchers, engineers, and computer scientists.[30] Understanding the possible risks of using these technologies, from physiological harm to breaching of privacy and confidentiality with insecure devices, and how to mitigate any risks is also important. Other important issues to consider include patient anxiety with overuse of technologies, health data piracy, self-diagnosis resulting from overreliance on self-monitoring, and patients not seeking help appropriately. These technologies should be used only as complementary tools in the treatment and prevention of health conditions and disease and should not be used in isolation by patients who self-diagnose and self-manage without consulting a health professional. 

Notably, among the nine schools ranked for the first time, WP Carey School of Business at the Arizona State University is the first US institution to take part in the ranking, having entered at 82.

Instant Heart Rate by Azumio.[31] A free app downloadable to both Apple and Android operating systems that measures heart rate and displays a monitoring strip. As well as helping users accurately track their heart rates, the app is capable of detecting irregular rhythms when palpitations occur. 

Sleep Time by Azumio.[32] A free app that monitors sleep patterns, sleep efficiency, and also acts as an alarm clock. Users can know how often they go into light and deep sleep, and recognize how much of these types of sleep will be necessary for them to feel rested, thereby quantifying the amount of true sleep they need and not just how long they should stay in bed. 

Bellybio Interactive Breating by RelaxLine.[33] A free app that helps users pace their breathing to achieve calmness. Placing the mobile phone against the abdomen, users can follow the sounds emitted to practise deep, abdominal breathing using this simple yet surprisingly effective tool. 

毫不奇怪,信贷具有“助周期性”。当资产价格一片繁荣时,乐观的贷款机构倾向于发放更多贷款,进而加剧市场的狂欢。当资产价格下跌时,贷款机构会控制风险,有时这种做法会加速下跌。
We will maintain ethical conduct and moral integrity at all times.

In terms of salary three years after graduation, Germany leads the way for masters in management programmes, with three schools in the top four. Graduates of WHU Beisheim have the distinction of earning the highest salary, at $98,123 on average.
STONINGTON, CONN.
Lori Steele
The big winners over the past year in Arizona were the construction and leisure/hospitality industries, which both added more than 10, 000 jobs. Other fast-growing sectors include business services, financial activities and education and health services.
3. The root cause of eczema has finally been identified. Scientists have tracked down a series of proteins and molecular pathways that lead to this insufferable skin problem, revealing that the protein filaggrin isn't the sole culprit we thought it was.
去年此时,罗丝·麦高恩以强奸罪控告制作人哈维·韦恩斯,在娱乐圈引发轩然大波,众多控告纷至沓来。

Discernment to determine whether a particular app, wearable, or sensor can be effective.
Expertise and experience to guide patients on the use of technology.
Partnership with patients in pursuit of optimal health through technology use.
Trials to closely monitor benefits and drawbacks.
Humility to recognize that patients may know and invest much more time than physicians in looking for these tools.34

Conclusions
Based on today’s rapid pace of development and public enthusiasm for the technology marketplace, health apps, wearables, and sensors will soon become integral to our patients’ pursuits of good health and will need to be integrated in clinical practice. Physicians must be active agents in these evolutionary times, guiding patients, advocating for evidence to support the use of technologies, and participating in the development and incorporation of technology in patient wellness journeys. Through clinical stewardship and partnership with patients, physicians can use their expertise and experience to guide the growth of innovations into mainstream health care.

Competing interests
Dr Ho receives no personal financial compensation as the principal investigator of TEC4Home (Telehealth for Emergency-Community Continuity of Care Connectivity via Home Tele-monitoring), a project funded by a Canadian Institutes of Health Research grant. This grant is matched by the Michael Smith Foundation for Health Research and the BC Ministry of Health, with additional support provided by TELUS Health and Sentrian. TELUS Health, Cisco, and Avizia have also provided equipment for display in Dr Ho’s Demonstration and Simulation Studio for Health (DaSSH) at UBC. Mr Yao and Dr Lauscher have no competing interests to declare.


2016年智能家居销量或翻番


References

1. Cision PR Newswire. Fifth annual Pulse of Online Health survey finds 66% of Americans eager to leverage digital tools to manage personal health. Posted 24 February 2015. Accessed 28 August 2017. www.prnewswire.com/news-releases/fifth-annual-pulse-of-online-health-survey-finds-66-of-americans-eager-to-leverage-digital-tools-to-manage-personal-health-300039986.html.

2. Swan M. Emerging patient-driven health care models: An examination of health social networks, consumer personalized medicine and quantified self-tracking. Int J Environ Res Public Health 2009;6:492-525.

3. Gao Y, Li H, Luo Y. An empirical study of wearable technology acceptance in healthcare. Ind Manag Data Syst 2010;115:1704-1723.

4. Kim KJ, Shin DH. An acceptance model for smart watches: Implications for the adoption of future wearable technology. Internet Res 2015;25:527-541.

5. West JH, Hall PC, Hanson CL, et al. There’s an app for that: Content analysis of paid health and fitness apps. J Med Internet Res 2012;14:e72.

6. Abroms LC, Padmanabhan N, Thaweethai L, Phillips T. iPhone apps for smoking cessation: A content analysis. Am J Prev Med 2011;40:279-285.

7. Cowan LT, Van Wagenen SA, Brown BA, et al. Apps of steel: Are exercise apps providing consumers with realistic expectations? A content analysis of exercise apps for presence of behavior change theory. Health Educ Behav 2013;40:133-139.

8. Azar KM, Lesser LI, Laing BY, et al. Mobile applications for weight management. Am J Prev Med 2013;45:583-589.

9. Breland JY, Yeh VM, Yu J. Adherence to evidence-based guidelines among diabetes self-management apps. Transl Behav Med 2013;3:277-286.

10. Lyons EJ, Lewis ZH, Mayrsohn BG, Rowland JL. Behavior change techniques implemented in electronic lifestyle activity monitors: A systematic content analysis. J Med Internet Res 2014;16:e192.

11. Lewis ZH, Lyons EJ, Jarvis JM, Baillargeon J. Using an electronic activity monitor system as an intervention modality: A systematic review. BMC Public Health 2015;15:585.

12. Bort-Roig J, Gilson ND, Puig-Ribera A, et al. Measuring and influencing physical activity with smartphone technology: A systematic review. Sports Med 2014;44:671-686.

13. Rhodes RE, Yao CA. Models accounting for intention-behavior discordance in the physical activity domain: A user’s guide, content overview, and review of current evidence. Int J Behav Nutr Phys Act 2015;12:1-14.

14. Chen M, Gonzalez S, Vasilakos A, et al. Body area networks: A survey. Mob Networks Appl 2011;16:171-193.

15. Appelboom G, Camacho E, Abraham ME, et al. Smart wearable body sensors for patient self-assessment and monitoring. Arch Public Health 2014;72:28.

16. Chan M, Estève D, Fourniols JY, et al. Smart wearable systems: Current status and future challenges. Artif Intell Med 2012;56:137-156.

17. Alemdar H, Ersoy C. Wireless sensor networks for healthcare: A survey. Comput Networks 2010;54:2688-2710.

18. Haberman ZC, Jahn RT, Bose R, et al. Wireless smartphone ECG enables large-scale screening in diverse populations. J Cardiovasc Electrophysiol 2015;26:520-526.

19. Ferdman DJ, Liberman L, Silver ES. A smartphone application to diagnose the mechanism of pediatric supraventricular tachycardia. Pediatr Cardiol 2015;36:1452-1457.

20. Baquero GA, Banchs JE, Ahmed S, et al. Surface 12 lead electrocardiogram recordings using smart phone technology. J Electrocardiol 2015;48:1-7.

21. Wootton R. Twenty years of telemedicine in chronic disease management—An evidence synthesis. J Telemed Telecare 2012;18:211-220.

22. Flodgren G, Rachas A, Farmer A, et al. Interactive telemedicine: Effects on professional practice and health care outcomes. Cochrane Database System Rev 2015;(9):CD002098.

23. Mortara A, Pinna GD, Johnson P, et al. Home telemonitoring in heart failure patients: The HHH study (Home or Hospital in Heart Failure). Eur J Heart Fail 2009;11:312-318.

24. Dar O, Riley J, Chapman C, et al. A randomized trial of home telemonitoring in a typical elderly heart failure population in North West London: Results of the Home-HF study. Eur J Heart Fail 2009;11:319-325.

25. Chaudhry SI, Mattera JA, Curtis JP, et al. Telemonitoring in patients with heart failure. N Engl J Med 2010;363:2301-2309.

26. Koehler F, Winkler S, Schieber M, et al. Impact of remote telemedical management on mortality and hospitalizations in ambulatory patients with chronic heart failure: The Telemedical Interventional Monitoring in Heart Failure study. Circulation 2011;123:1873-1880.

27. Kitsiou S, Pare G, Jaana M. Effects of home telemonitoring interventions on patients with chronic heart failure: An overview of systematic reviews. J Med Internet Res 2015;17:e63.

28. TEC4Home Healthcare Innovation Community. Supporting heart failure patient transitions from acute to community care with home telemonitoring technology: A protocol for a provincial randomized controlled trial (TEC4Home). JMIR Res Protoc 2016;5:e198. 

29. Yao C, Ho K. Mobile sensors and wearable technologies. In: Amelung VE, Stein V, Goodwin N, et al., editors. Handbook integrated care. Cham, Switzerland: Springer; 2017.

30. Ho K, Borycki E, Kushniruk A, et al. The health perspective in using digital media for health and wellness. Presented at the IEEE International Digital Media Industry Forum, Boston, MA, 4-6 July 2016.

31. Azumio Inc. Instant heart rate. Accessed 28 August 2017. www.azumio.com/s/instantheartrate/index.html. 

32. Azumio Inc. Sleep time. Accessed 28 August 2017. www.azumio.com/s/sleeptime/index.html. 

33. RelaxLine. BellyBio. Accessed 28 August 2017. https://itunes.apple.com/ca/app/bellybio-interactive-breathing/id353763955?mt=8.

34. Ho K. How health information technologies are enhancing health of patients and their doctors. Presentation at the Alberta Medical Association 2015 Spring Representatives Forum, Edmonton, AB, 13 March 2015.


当她向经理咨询的时候,凯说,当他们的员工开始不经常和他们讲话,无论是更新工作内容,询问意见还是仅仅打个招呼,他们中的许多人都能警觉地察觉到一些事情。正如凯总结地那样:“你开始不做那些你日常维持社交关系的事情了。”
Six regions recorded GDP growth less than 7 percent, with China's north-eastern rust belt Liaoning province at the bottom with negative growth.
据行业估计,到2020年,我国年度票房有望达到1000亿元人民币。
Consumer Electronics Show
US schools are rebuilding their strength in this ranking, with their number increasing to 51. This had dropped below 50 for the first time in 2016, down to 47. Six of the eight new or returning schools are from the US.
根据近日发布的《第13次国际年度住房负担能力调查:2017》显示,这三座城市高居世界最不可购性房屋市场的前三甲。
《法律与秩序:特殊受害者》(Law & Order: SVU):NBC频道的这部电视剧上一季中的危机仿佛是从肥皂剧中搬来,发生了各种大事,奥利维亚(Olivia,玛莉丝卡·哈吉塔[(Mariska Hargitay]饰)经历了许多危险——喜欢跟踪的变态强奸犯,折磨人的婚外恋,新生婴儿,现在这一切终于平息下来。在今年的第16季中,侦探们回到了重要的性犯罪上,其中一集的灵感来自雷·赖斯(Ray Rice),讲述的是从监控录像中看到一个著名体育广播员殴打自己的妻子。
To Japanese creators Kazutaka Kurihara and Koji Tsukada for developing the SpeechJammer, a device that uses delayed auditory feedback to shut up participants in a discussion. This kind of system has been used in speech therapy to reduce stuttering among those with that particular speech disturbance.
After weeks of nail-biting auditions and five days of tense semi-finals, Britain’s Got Talent picked one of the 11 acts to be the 2014 champion.
Sinta Nuriyah

Kendall Ho, MD, FRCPC, Christopher Yao, MSc, Helen Novak Lauscher, PhD. Part 2: Health apps, wearables, and sensors: The advancing frontier of digital health. BCMJ, Vol. 59, No. 10, December, 2017, Page(s) 503-506 - Clinical Articles.



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The city of 21 million people recorded 1.86 trillion yuan in total consumption in 2015, marking a yearly rise of 8.7 percent. Consumption contributed over 70 percent to the city's GDP growth.
立场:提倡“自觉资本主义”
Length of program: 13 to 15 months
Local educational authorities have since revoked Zhengzhou Boqiang New Idea Life Training School's license and launched an investigation into its record. Hauntingly, the school's website remains online, replete with photos of students in camouflage uniforms performing drills and attending what the site labels "wonderful lectures."

他表示,2017年的目标是航班整体准点率维持在75%左右。

  • Only the first three authors are listed, followed by "et al."
  • 买房开发票竟要自垫税款 地税局:我们没办法
  • 5月房价上涨城市增至48个 楼市难言全面回暖


去年年末,世界卫生组织宣布,寨卡病毒不再是全球紧急公共卫生事件。然而,人们才刚刚开始认识到这种病毒对婴儿及其未来几十年生活的影响。在巴西东北部,人们首次发现了病毒与小头畸形等出生缺陷之间的联系,家庭竭力为患病婴儿提供最好的生活。研究人员希望通过研究在巴西出生的一对双胞胎,来寻找病毒对胎儿影响的线索。这对双胞胎中,一个有出生缺陷,另一个没有。
5. The 2012 Ig Nobel Chemistry Prize

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