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Themed collection Coronavirus articles - free to access collection

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Editorial

Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research

单词stable 联想记忆:
The ability of customers to air their dirty laundry to the world via Twitter and Facebook has already changed the customer service game. A 2012 Nielsen survey shows more than half of all customers now turn to social media for redress; meanwhile, some 81% of Twitter users expect a same-day response to questions and complaints. But this fall, things got even more interesting: On Sept. 2, British Airways passenger Hasan Syed spent an estimated $1,000 to purchase several promoted Tweets blasting the company for losing luggage. With paid social media now in customers' arsenal, 2014 may mark the beginning of the end of abysmal customer service at major airlines, credit card companies, banks, and other repeat offenders, characterized by endless phone wait times and those automated "phone trees" (i.e., "Press 1 for English, 2 for Spanish, 3 to waste your entire afternoon on hold ...").

Graphical abstract: Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
Editorial

Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?

不过,在这一反弹中也出现了奖金数额的下滑:去年的平均年终奖是12821元人民币(合1861美元),比2015年多了大约2000元人民币,却仍比2014年的平均值少了800元人民币。在奖金缩水的被调查者中,逾四分之一的人将原因归结为公司业绩太差。
Take the intriguing reintroduction of “unfeigned regards” — last big in the 18th century and now found on emails from Indian help centres. But the winning sign-off, at the bottom of a message sent one Friday, was: “weekend well”. I nearly awarded it second prize for the best noun pretending to be a verb, though at the last minute this award was snatched by a consultant overheard saying: “Can we cold towel that?”

Graphical abstract: Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
Open Access Accepted Manuscript - Highlight

Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities

Open Access Perspective

Soft matter science and the COVID-19 pandemic

But McGowan has slammed the movement as 'bull****' in today's Sunday Times Magazine, which comes the day after Judge Brett Kavanaugh was sworn in as a Supreme Court justice in the face of historic sexual assault allegations he denies.

Graphical abstract: Soft matter science and the COVID-19 pandemic
From the themed collection: 北京昌平区借大数据治城市病
Open Access Perspective

Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective

根据花旗居屋(Citi Habitats)提供的数据,在布鲁克林拟于明年投放市场的6527套新出租屋中,有1442套分布在贝德福德-斯图文森(Bedford-Stuyvesant)、布什维克(Bushwick)和克林顿山(Clinton Hill)。就在不久前,这些社区都还被视为不热门的地区。

Graphical abstract: Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
Perspective

Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic

韩云平称,去年质检总局组织了两次大规模的检查,涉及超过5300批的进口消费品,例如空气净化器、汽车刹车块、家用电器和服装等,其中超过1500批的商品不合格。
A total of 3,077 new cases of HIV infection took place in colleges and universities across China in 2017, according to the National Health Commission (NHC) at a press conference on Friday.
This year's new college grads entering the workforce are being offered an average monthly salary of 4,014 yuan ($582), and about one-third of them chose to work in first-tier cities, according to survey results released by zhaopin.com, a Chinese online recruitment service provider.
亲朋好友称Ross是一个充满活力有梦想的女孩子,她走到哪里,都会被她点亮。她去世后几天,她的母亲Alicia Jesquith告诉记者,女儿突然离世,她需要一个答案。

Graphical abstract: Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
Perspective

Trends and targets in antiviral phototherapy

[in'k?rid?m?nt]
The top 10 Weibo celebrities now have a combined 40 million followers. One of the most famous online figures, Papi Jiang, already signed a contract for video ads worth a staggering 22 million.
Peace and love for you at New Year from all your students.祝老师新年充满平安和爱。
n. 诱惑,引诱

Graphical abstract: Trends and targets in antiviral phototherapy
From the themed collection: 自贸区红利吸引智能企业转移聚集
Minireview

A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays

据国家新闻出版广电总局介绍,自2003年以来,中国这一世界第二大电影市场的票房总额平均逐年增长35%。仅仅在2015年,这一数字就猛增了48.7%。

Graphical abstract: A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
From the themed collection: 18种情形失信企业将被列入黑名单
Minireview

Novel biosensing methodologies for ultrasensitive detection of viruses

节目14 歌曲《报喜》,陈慧琳

Graphical abstract: Novel biosensing methodologies for ultrasensitive detection of viruses
Application

Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug

有趣的是,金砖国家减持美国政府债券之时正值美国经济活动缓慢回升之际。
Criminal gangs have been difficult to catch, however, because illegal meats are often hidden among other produce such as fruit and vegetables, and lorry drivers are often bribed to deny any knowledge of it.

Graphical abstract: Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
Open Access Review Article

ACE2 as a potential therapeutic target for pandemic COVID-19

If you don't, you need to trade Boogie Cousins and all those veterans you signed over the past two offseasons.
Apple CEO Steve Jobs poses with the new iPhone 4 during the Apple Worldwide Developers Conference in San Francisco, California in this June 7, 2010

Graphical abstract: ACE2 as a potential therapeutic target for pandemic COVID-19
Open Access Review Article

Diagnostic technologies for COVID-19: a review

Get ready to see ads from the neighborhood pub on Twitter
Domestic action movie "Wolf Warrior II" was top on the list and became the country's highest-grossing film ever, raking in 5.68 billion yuan in ticket sales.

Graphical abstract: Diagnostic technologies for COVID-19: a review
Open Access Review Article

Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review

阿里巴巴旗下品牌淘宝位居第二,品牌价值429亿美元,超过了中国移动、百度和中国工商银行。
经济运行缓中趋稳、稳中向好;
n. 前辈,前任,原有事物
re再+membr[=member]记得+ance→回忆;记忆力

Graphical abstract: Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
Open Access Review Article

An overview of key potential therapeutic strategies for combat in the COVID-19 battle

It is already illegal for employers to discriminate on the basis of race, color, sex, nationality, religion, age, or disability. But a majority of states still don't provide protection to LGBT individuals in the workplace. Apple (AAPL, Fortune 500) CEO Tim Cook wants to put an end to this discrepancy. In a November Wall Street Journal op-ed entitled "Workplace Equality Is Good for Business," Cook urged the passing of a federal law to protect workers from discrimination based on sexual orientation.

Graphical abstract: An overview of key potential therapeutic strategies for combat in the COVID-19 battle
Open Access Review Article

Potential repurposed SARS-CoV-2 (COVID-19) infection drugs

你如何知道你需要喝水了?这有一系列的诱因:嘴唇发干、头晕、头痛、尿量低和口渴。然而,这种智能瓶能在你的身体意识到缺水前就提醒你。
Sweden

Graphical abstract: Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
Open Access Review Article

Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale

Starting a business can wreak havoc on the owner’s personal life. While all the above tips are necessary for success, taking care of yourself mentally and physically is also imperative. Exercise, sleep and diet play a central role in ensuring you implement these policies successfully. All of them drive attitude, motivation and relationships.

Graphical abstract: Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
Review Article

In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections

就零工经济的命运来说,英国将是一个值得关注的关键国家。英国政府将对一份关于英国法律是否跟得上这一新趋势的独立评估做出回应。考虑到政府的脆弱性和耗时的英国退欧进程,现在似乎不太可能出台大胆的政策行动——无论是支持还是反对在线劳动力平台。

Graphical abstract: In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Review Article

Antiviral drug discovery: broad-spectrum drugs from nature

The stomach-churning finding is not the first to be exposed in the area. Police in Guangxi, along China's border with Vietnam, have stepped up anti-smuggling operations over the last year and have raided seven illegal food processors.
普京对俄罗斯经济做出积极评价。他说,经济已渡过危机,至少渡过了危机的高峰。
['s?m?ri]
5. Gross warns: 'Ponzi Scheme! Tipping Point! Credit Supernova!'

Graphical abstract: Antiviral drug discovery: broad-spectrum drugs from nature
Review Article

Influenza neuraminidase: A druggable target for natural products

Paris (AFP) - Some 1,400 people living in France have either joined the jihadist cause in Syria and Iraq or are planning to do so, Prime Minister Manuel Valls said Monday.
4. Slacking at school
1.无论在什么情况下都不要问出租车司机,对于今年夏天伦敦的奥运会有多么激动。不是说他会勉强或尴尬地发表个人意见,而是你根本就不该问这个问题。
年度最佳单曲:米兰达·兰伯特《Over You》
工业企业利润由上年下降2.3%转为增长8.5%;

Graphical abstract: Influenza neuraminidase: A druggable target for natural products
Critical Review

Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle

韩美林在他的社交媒体上表示,他只设计了吉祥物的水墨画原始版本,对3D版并不知情。某网友对此回应了这位德高望重的艺术家:“我们当然相信这只丑猴和韩大师无关。”
n. 有价证券;担保;保证人;抵押物(security的

Graphical abstract: Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
Critical Review

The role of biosensors in the detection of emerging infectious diseases

时间:2009-09-16 编辑:vicki

Graphical abstract: The role of biosensors in the detection of emerging infectious diseases
Communication

Quantitative determination of mechanical stability in the novel coronavirus spike protein

但是,只要快速扫一眼日益变化的天际线,我们就能发现一个令人沮丧的现实:那些光鲜亮丽的新大厦,未能提供大部分纽约人买得起的房型。“我们正在修建的房屋,跟我们需要修建的房屋之间存在着脱节,”房地产估值公司米勒·塞缪尔(Miller Samuel)的总裁乔纳森·J·米勒表示,“2015年,这一现象会更加明显。”

Graphical abstract: Quantitative determination of mechanical stability in the novel coronavirus spike protein
From the themed collection: 上海多措并举筹措租赁房源
Communication

Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations

此外,排名前列的城市的“成本”、“文化与居民生活”两项指标普遍不高。在满足民众需求、并提供高质量生活方面,中国的“机遇城市”仍然面临挑战。
"I don't know what happened," Lowry said. "I just know I got a call for offensive foul. It happens. It's the NBA. That's all I can say about it."
推特方面日前表示,在今年8月弗吉尼亚州夏洛特维尔爆发种族骚乱后,奥巴马发布的一条推文是今年转推量第2多的推文,转推量达170万次以上。
Swift has also been having quite the year, claiming the No. 2 spot with $80 million. More than a year after the launch of 1989—the top release of 2014 with over 3.6 million copies sold—her latest single, “Wildest Dreams,” has ascended to the top of the charts, boosted by a music video with Scott Eastwood. But it was the beginning of her epic 1989 World Tour that placed her so close to the top of this list.

Graphical abstract: Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
Communication

MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling

不过,企业在年终奖上的吝啬,造成的影响可能不仅仅是破坏员工的春节假期,还可能回头反噬雇主:39%的回复者表示如果年终奖不能恢复正常,他们会另谋高就,这一比例比2015年高了2.3个百分点。
这个系列的特制镜框和太阳墨镜以“DVF|为谷歌眼镜设计”为标签,价格高达1,600美元以上。迄今为止,谷歌已经和雷朋(Ray-Ban)眼镜的生产商陆逊梯卡(Luxottica)以及其他几家提供时尚眼镜的公司如普拉达(Prada)等展开过合作。它还招募了曾在艺术网站Art.com担任首席市场官的时尚总监艾维o罗斯来领导谷歌眼镜团队。
两队将于10月5日抵达深圳并将在深圳大运中心进行比赛。
Scientists confirmed Monday that a skeleton found under a carpark in the English city of Leicester was that of King Richard III, in a bizarre end to a 500-year-old historical mystery.

Graphical abstract: MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
Communication

Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses

单词fatigue 联想记忆:
HOUSE OF CARDS (Netflix, Feb. 27) Netflix’s political grand guignol gets a 13-episode third season. Kim Dickens of “Treme” joins Kevin Spacey and Robin Wright in the cast, and two members of Pussy Riot will make a guest appearance.

Graphical abstract: Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
Communication

Inhibition of SARS coronavirus helicase by bismuth complexes

007系列电影主题曲第五名:保罗·麦卡特尼和Wings乐队--《生死关头》
"All I got was an extra hour on the bus to work, but I can't get a seat at the stadium," she said as she directed cars toward a mall's parking garage in Rio's wealthy southern zone.
低效的邮件沟通包括很多内容,从不及时回复邮件,到表达不清等问题都包括其中。如果你没有及时回复邮件的好习惯,你可能会错过重要的会议或者是截止日期,造成推迟以及迷惑,被认为是不专业的。
With a growing need for someone to block and tackle Apple’s raiders and (given its tax investigation in Europe) regulators, Mr Cook’s focus on people, strategy and execution — rather than products — finally started to look like an advantage.
Mr Erdogan, who has also benefited domestically from the row with Mr Rutte, has sought to broaden his diplomatic dispute to take on all of the EU, particularly Germany, which has had similar run-ins with Ankara over campaigning in Germany’s large Turkish community.

Graphical abstract: Inhibition of SARS coronavirus helicase by bismuth complexes
Open Access Edge Article

Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning

为期三天的"中国发展高层论坛2016"近日在北京开幕。
课程安排:每隔一个周末在芝加哥上课,共计大约18门课程,包括4门选修课。学员在芝加哥住校学习3周,在香港和伦敦分别学习1周。
新兴市场出口额(以美元计算)下滑完全是一种价格效应,受到大宗商品价格下降的拖累。从数量上看,新兴市场出口自2014年以来一直持续上升,即便同比年增长率已放缓至2%左右——远远低于全球金融危机前后的两位数增长率,如第二张图表所示。

Graphical abstract: Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
Open Access Edge Article

A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers

It grows naturally into the mold's shape.
“我们需要做市长希望大家做的事——建造更多住房,”纽约房地产委员会主席史蒂芬·斯皮诺拉(Steven Spinola)说,但是,“如果数据上不可行,如果收回来的租金低于建筑的维护成本,那你就不会这么做了。”

Graphical abstract: A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
Open Access Edge Article

Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods

The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.

Graphical abstract: Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
Open Access Edge Article

Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors

By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.

Graphical abstract: Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
Open Access Edge Article

Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir

年度故事将是纽约对911主谋穆罕默德(Khalid Sheikh Mohammed)的审判。
n. 精华,精锐,中坚份子
内衣秀以马戏表演开始,包括杂技,吞剑和踩高跷。然后贾斯汀比伯,蕾哈娜和布鲁斯马斯登场。

Graphical abstract: Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
Open Access Edge Article

Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes

2017年,衡量工业品出厂价格、反映经济活力的主要指标--生产者物价指数(PPI)上涨6.3%,结束了自2012年以来的连续下降态势。2016年PPI下降1.4%。
Since the establishment of Avic 1 and Avic 2 in 1999, which really marked the beginning of China’s push into the commercial aerospace market, there has been no doubt about China’s intent and the direction it wants its industry to take. But the pace at which it would achieve this ambition was less uncertain. Almost 20 years on, things have become much more clear, and there is now little doubt that China is well on its way to succeeding where several other countries have failed in becoming a full-fledged player in the large commercial aircraft manufacturing sector, with the potential to disrupt the long-standing duopoly of Airbus and Boeing.
5.You Aren't Making Enough Money to Pay Your Bills

Graphical abstract: Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
Accepted Manuscript - Paper

A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring

From the themed collection: 武汉启用新存量房买卖和居间合同
Open Access Paper

Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)

US News also offers subject-focused rankings, which include popular fields such as computer science, economics and business and engineering.

Graphical abstract: Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
Paper

A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood

立场:为禁止员工在家上班进行辩解

Graphical abstract: A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Open Access Paper

Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations

2014年,尽管汽车销量自2007年以来首次超过1600万辆,但占据媒体头条的还是各类召回事故。在召回舞台上最活跃的是通用汽车公司,由于不断曝出点火开关故障,通用今年已经召回了几百万辆汽车。这家汽车制造商选择勇敢曝光自己的失误,并公开发布了一份自查报告。而日本气囊生产商高田公司却对“气囊门”三缄其口,转而把补救措施留给其深陷困境的客户本田和丰田来实施。有问题的气囊爆炸后,会向驾驶室弹出致命碎片。
该新规还专门针对出租车服务作出规定。

Graphical abstract: Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
From the themed collection: 四川陶瓷卫浴产业格局之变
Open Access Paper

The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives

adj. 可能的,潜在的
11月,财新-Markit制造业采购经理人指数(PMI)从10月的51%降至50.8%,接近区分扩张和收缩的50%大关。此前,路透社(Reuters)对经济学家进行调查得出的预测中值曾预计,制造业PMI将降至50.9%。
同时,美国Rapper歌手Eminem被证明是“复出王”,摘得最佳Hip Hop歌手奖。”The Lose Yourself ”的创作者与Hip Hop的新面孔相互竞争,包括Drake, Future, Kendrick Lamar and Post Malone。
9.亲爱的贵客们,我们希望英国能为你们贡献一个美好的夏天,这个夏天包括了顶尖的国际赛事、先进的设施、有趣的娱乐、以及汇集了几个世纪的艺术建筑精华的文化遗产。如果你最终只收获了四张卓著国际中心的摔跤比赛门票,好吧,祝你下次好运。

Graphical abstract: The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
Open Access Paper

Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease

除了这些理论之外,还有传统经济学家用来误导美国的坏的统计数据:最恶劣的是GDP,它在衡量美国长期增长的时候是一个狭窄的、误导人的指标。其次,我们对短期数据(每日收盘情况、季度业绩、年度回报等)的执迷正在阻碍美国的长远增长。
'Fruitvale Station' represents another remarkable feature debut, by the director Ryan Coogler. Its subject matter-the fatal shooting of Oscar Grant, a black, unarmed 22-year-old by a white transit cop in Oakland, Calif.-might have made a documentary. Mr. Coogler had the better idea of exploring it as a dramatized, and to a considerable extent fictionalized, account of the day in Oscar's life that preceded his death. He's played by Michael B. Jordan, whose performance can break your heart or fill it with joy, sometimes simultaneously.

Graphical abstract: Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
Open Access Paper

Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro

My bet is those forces — and America’s CEOs — will continue to temper the president’s trade tantrums in the short term. But there are lots of people baying for Chinese trade blood in Washington these days.
世界各国同意将地球升温控制在3.6华氏度以内,这需要在未来大约30年里,抑制温室气体排放,之后基本停止排放。科学家表示,如果在本世纪,排放量继续按照当前趋势发展,地球温度将比前工业化时代水平提高10华氏度,那将与人类文明当前的形式不再兼容。

Graphical abstract: Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
Open Access Paper

Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein

The gig economy

Graphical abstract: Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Paper

Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide

历届“邦女郎”性感比拼
“I am so overwhelmed and elated that fur has been banned from London Fashion Week! Progress!” Faith wrote.
瑞士洛桑国际管理发展学院在针对所有在职管理人员的开放招生课程排行榜中拔得头筹,在针对企业客户的定制课程排行榜中攀升了两位,升至第二。西班牙Iese商学院在定制课程排行榜上继续保持榜首位置,在开放课程排行榜中仍位居第二。
Coca-Cola CEO Muhtar Kent

Graphical abstract: Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
Open Access Paper

Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses

re再次+form形状→再形成→改革,改造
我国发展到现在这个阶段,不靠改革创新没有出路。我们拥有世界上数量最多、素质较高的劳动力,有最大规模的科技和专业技能人才队伍,蕴藏着巨大的创新潜能。

Graphical abstract: Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
Open Access Paper

The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor

2016年国家公务员考试报名人数已经超过去年,仅周二一天,符合考试条件的报考人员就达到13.2万人以上,这是单日报考人数最高的一天。
In a vote by Sina Weibo,China's Twitter-like website, 58.5 percent of people "liked" the ink painting version of the monkey, only 14.4 percent like the front view of the 3D version, while 12.5 percent want to "change its clothes", supposedly meaning they don't like the colors.
“The Diary of a Teenage Girl” (Marielle Heller)

Graphical abstract: The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
Open Access Paper

Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study

In the foreseeable future, China will see the boom of enterprises in tertiary industry. Related majors, including law, journalism and communication, and management, are expected to play a bigger role, according to the report.
3. 丹·韦斯(Dan Weiss),《14》,Pi Recordings。《14》的内容如此丰富,整张专辑的作曲由鼓手丹·韦斯一手包办:细节丰富的室内乐,前卫的啸叫,新音乐无词人声与北印度音乐。相比这个宏大的音乐参照系,更令人印象深刻的是,韦斯集结了12名同行乐手,把所有音乐元素融汇为流畅的整体。
《花千骨》

Graphical abstract: Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Open Access Paper

Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework

本周二在竞选的最后阶段,罗姆尼还前往俄亥俄州和宾夕法尼亚州,希望能在这些摇摆州取得选票支持。奥巴马竞选阵营这边,副总统拜登也前往了俄亥俄州,奥巴马本人留守芝加哥。
格温妮丝·帕特罗(Gwyneth Paltrow)曾出演《莎翁情史》(Shakespeare in Love)获最佳女主角奖,并成为好莱坞明星。为了避免在发表获奖感言时出现混乱,她却把小金人藏了起来,因为“这东西吓坏我了”。

Graphical abstract: Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
Open Access Paper

Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach

Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.

Graphical abstract: Several coumarin derivatives and their Pd(ii) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Open Access Paper

Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors

Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.

Graphical abstract: Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Open Access Paper

Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins

Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.

Graphical abstract: Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Open Access Paper

Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform

两岸是骨肉同胞,血浓于水,不管岛内形势如何变化,都割断不了两岸的亲情,也改变不了我们维护两岸关系和平发展的决心和诚意。
On the US, Rabobank said it was cautious on the outlook following the election as president this month of Donald Trump.
当很多千禧一代很难找到工作或在低技能岗位上将就时,凭着项目本身与公司合作伙伴的联系以及校友网络,这些管理学硕士项目的毕业生获得了很高的就业率。

Graphical abstract: Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
Open Access Paper

A modular microarray imaging system for highly specific COVID-19 antibody testing

['serim?ni]
卡梅隆·安东尼

Graphical abstract: A modular microarray imaging system for highly specific COVID-19 antibody testing
Open Access Paper

Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms

Despite the confusion, executive producer Ed Razek has commended the Chinese partners as “wonderful and enthusiastic hosts.”
1.手指存储器
The PPI has been negative for 44 consecutive months, reflecting excess supply of housing materials and raw materials, and overcapacity in heavy industry.

Graphical abstract: Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
From the themed collection: 二季度武汉155个房地产项目入市
Open Access Paper

Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening

“Since these developments will not fade overnight, there is little hope for a trade revival in 2017,” says Mr Leering.

Graphical abstract: Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Open Access Paper

Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations

A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.

Graphical abstract: Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
Open Access Paper

Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets

反对:影片可能太过非主流,不具有获得大奖的影响力。
怎么做煎饼?

Graphical abstract: Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
Open Access Paper

A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation

Criminal gangs have been difficult to catch, however, because illegal meats are often hidden among other produce such as fruit and vegetables, and lorry drivers are often bribed to deny any knowledge of it.
vt. 保卫

Graphical abstract: A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
Open Access Paper

An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19

3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.

Graphical abstract: An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
From the themed collection: 报告显示消费者购房行为趋向理性
Open Access Paper

Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies

据行业估计,到2020年,我国年度票房有望达到1000亿元人民币。
当城市规划部门明年初(2015年——译注)提出初步的建议方案时,布鲁克林的东纽约(East New York)地区将被列为试点。随后,重新区划进程就将在该处全市最穷社区之一内展开。而紧随其后的,将是针对皇后区的西法拉盛(Flushing)的提案。

Graphical abstract: Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
Paper

Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material

待售房产:一栋带有三间卧室和三间半浴室的河滨当代住宅
2010 U.S. unemployment rate (average): 10.2%

Graphical abstract: Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
Open Access Paper

A facile assay for rapid detection of COVID-19 antibodies

Neumann, Silbermann and Sharp are three of 66 billionaires under 40 years old, a record for the Forbes list.

Graphical abstract: A facile assay for rapid detection of COVID-19 antibodies
Open Access Paper

Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses

Plans to open 20,000 specialist football schools in 2017, aimed at training young players and cultivating talent, are part of the government's latest plan to advance China's ability to compete on the global pitch.
Feud: Bette and Joan
科学家改良光合作用提高作物产量
单词romantic 联想记忆:

Graphical abstract: Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
Open Access Paper

Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2

(Actually, JetBlue wasn’t the absolute worst airline for departure delays the last three holiday seasons. That crown went to Comair, a regional carrier for Delta Air Lines

Graphical abstract: Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Open Access Paper

Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease

elite
Mila Kunis just keeps on raking in those sexy titles.
波比的父亲,28岁的安顿,承认他一开始对波比的风格路线有所顾虑,不过现在他已经欣然接受这件事了。

Graphical abstract: Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
Open Access Paper

Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19

[.dem?n'strein]
stylish

Graphical abstract: Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
Paper

Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties

该剧在拍摄武术场景时使用的慢动作手法赢得不少好评。
瑞士洛桑国际管理发展学院在针对所有在职管理人员的开放招生课程排行榜中拔得头筹,在针对企业客户的定制课程排行榜中攀升了两位,升至第二。西班牙Iese商学院在定制课程排行榜上继续保持榜首位置,在开放课程排行榜中仍位居第二。

Graphical abstract: Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
Open Access Paper

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.

Graphical abstract: Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Paper

Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract

n. 同伴,伙伴,合伙人

Graphical abstract: Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Open Access Paper

Anti-HIV drug repurposing against SARS-CoV-2

9、另一地球
你可能已经在使用谷歌日历了,但你使用的方式是否正确呢?告诉你一个秘诀:只要把在那个日子和那个时候会真正发生的事情记录在谷歌日历上就行。同时利用iPhone提醒记住那些时间敏感性不太强的事情(即不是那些精确到小时和分钟的事情)。遵循这一战略有助于你保持更清醒的状态。
vt. 抵押

Graphical abstract: Anti-HIV drug repurposing against SARS-CoV-2
Paper

Length-scale dependence of protein hydration-shell density

胡润百富榜创始人胡润表示,姚振华代表了一类新型的中国富人,他们的财富不是来自贸易或者制造业,而是来自金融市场操作。
源于:metal(n 金属),因为奖牌是金属做的
Life Is Strange
Why does beauty exist? To answer this question, Richard O. Prum, an ornithologist, is working to revive an idea advanced by Charles Darwin: the attractiveness of an animal to another of its species isn’t only tied to fitness and good genes. Rather, animals — especially birds in Dr. Prum’s work — are making subjective decisions. He hopes that evolutionary biologists will stop “explaining away desire.”

Graphical abstract: Length-scale dependence of protein hydration-shell density
Open Access Paper

High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus

18. 最有趣的道歉(并列)。11月18日,《好莱坞报道者》发表了一份1200多字的道歉,因为它的“奥斯卡女星圆桌会议”没有邀请非白人演员出席。很快,导演亚历克斯·普罗亚斯(Alex Proyas)和狮门公司就为新片《埃及众神战》(Gods of Egypt)中的演员缺乏多样性而道歉。
当小李子上台领取奖杯时,制片人哈维·韦恩斯坦兴奋地拍拍他的背,全场观众起立为他喝彩。

Graphical abstract: High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
Paper

A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor

这些,都只是纽约人2015年将会遇到的部分问题。而且,邻居家的儿子在圣诞节收到了新的爵士鼓,你又免不了要头疼了……
我去年就说过、今年要再强调的一点是:唯一比预测未来更不招人待见的事情就是公开自己的预言。
新年是这样美好的时光:炉火熊熊,花儿芬芳,醇酒飘香,殷殷祝福,美好回忆,

Graphical abstract: A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
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About this collection

The fruit is placed into the mold when it's young and undeveloped.
Dwight Howard

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